蛋白质工程与设计
Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science. Experimental Protein Engineering The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering.
中文| 2009 |页数:434 | ISBN:1032836687,1420076582 | PDF | 6.9 mb实验性蛋白质工程和计算性蛋白质设计是开发具有改变或新颖结构特性和生物功能的蛋白质的广泛但互补的策略。通过描述这两个领域的前沿进展,蛋白质工程与设计旨在培养一种协同的蛋白质科学方法。实验蛋白质工程本书的前半部分讨论了蛋白质工程的实验方法,并首先描述了几种用于蛋白质工程的高通量筛选平台。还讨论了用于多样性产生的关键技术。接下来的几章介绍了通过理性或组合方法设计的治疗剂、酶、生物材料和其他蛋白质的例子。本节最后一章介绍了非天然氨基酸在蛋白质工程中的应用。本站不对文件进行储存,仅提供文件链接,请自行下载,本站不对文件内容负责,请自行判断文件是否安全,如发现文件有侵权行为,请联系管理员删除。
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