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蒙古沙土鼠脑:线粒体功能、血管和病理生理状态

English | 2024 | ISBN-10: 3031695488 | 349 pages| Epub PDF (True) | 95 MB

The Mongolian gerbil brain lies in the anatomy of the blood vessels supplying blood to the brain. In all mammals, there is a special mechanism that compensates for the decreased blood flow to the brain in the case of development of stroke. This mechanism is missing in the gerbil and therefore makes the Mongolian gerbil a unique model for stroke. Dr. Mayevsky adopted the gerbil as a model for stroke and his laboratory uniquely studied the mitochondria in the gerbil brain under various pathophysiological conditions.

This book describes the history of the Mongolian gerbil in research, the brain energy metabolism and mitochondrial function and brain real-time monitoring systems used in gerbils, as well as the brain vasculature of the Mongolian gerbil. Further, the book includes chapters on brain multisite recording under brain perturbations, multiparametric responses to brain activation, and the effect of neuroprotectants on the gerbil brain.

中文|2024|ISBN-10:3031695488|349页|Epub PDF(True)|95 MB蒙古沙土鼠的大脑位于向大脑供血的血管的解剖结构中。在所有哺乳动物中,都有一种特殊的机制,可以在中风发生时补偿大脑血流的减少。沙土鼠缺乏这种机制,因此使蒙古沙土鼠成为中风的独特模型。Mayevsky博士采用沙土鼠作为中风模型,他的实验室在各种病理生理条件下对沙土鼠大脑中的线粒体进行了独特的研究。 本书介绍了蒙古沙土鼠的研究历史、沙土鼠使用的脑能量代谢和线粒体功能以及脑实时监测系统,以及蒙古沙土犬的脑血管系统。此外,本书还包括关于脑扰动下的脑多部位记录、对脑激活的多参数反应以及神经保护剂对沙土鼠脑的影响的章节。
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