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纳米载体在脑内给药中的应用

English | 2024 | ISBN-10: 9819728584 | 405 pages| Epub PDF (True) | 65 MB

This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The initial chapter of the book discusses complex brain disorders, the currently available therapies, and their limitations. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery. Further, it evaluates the development and role of different cell lines and animal models in brain research. Towards the end, the book reviews challenges, safety, toxicity, regulatory aspects, future possibilities, and constraints in the clinical translation of nanocarrier systems to treat neurological disorders. The book as such provides valuable information to neuroscientists, and researchers working in pharmaceuticals, nanomedicine, drug delivery research, and nanotechnology. ​

英文|2024|ISBN-10:9819728584|405页|Epub PDF(真)|65 MB 这本书介绍了纳米粒子作为克服血脑屏障的潜在药物递送载体。本书的第一章讨论了复杂的脑部疾病、目前可用的疗法及其局限性。这本书讨论了聚合物纳米粒子、脂质纳米载体、脂质体、无机纳米粒子、树枝状大分子和刺激响应性聚合物在靶向脑药物递送中的潜在应用。此外,它还评估了不同细胞系和动物模型在大脑研究中的发展和作用。最后,本书回顾了纳米载体系统治疗神经系统疾病的临床转化中的挑战、安全性、毒性、监管方面、未来可能性和限制。这本书本身为神经科学家以及在制药、纳米医学、药物输送研究和纳米技术领域工作的研究人员提供了宝贵的信息。​
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