癌症治疗中的纳米颗粒:创新与临床应用
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance. Additionally, it explores nanotechnology in radiation therapy, phototherapy modalities and bioengineered virus-like nanoparticles for diagnostics and therapeutics. The last section reviews the clinical applications and prospects, examining theranostic nanoparticles, the clinical translation of nanomedicine and the current limitations of cancer nanotherapy. It also addresses future directions in nanoparticle application, and examines the genotoxicity, immunotoxicity, cytotoxicity assessments, safety profiles, targeted drug delivery, and their role in viral oncogenesis. This book is a useful resource for researchers, clinicians and students in the fields of oncology and nanotechnology.
English | 2025 | ISBN:1032849177 | 345页| True PDF EPUB | 59.49 MB本书介绍了纳米颗粒在癌症治疗中的作用,强调了其在治疗、诊断和治疗策略开发方面的创新应用。本书的第一部分介绍了纳米颗粒在癌症疫苗和基因治疗中的应用。它主要讨论了聚合物纳米粒子作为纳米疫苗载体、用于免疫治疗的膜基纳米疫苗和使用纳米粒子的基因治疗技术。第二部分介绍了先进的纳米医学方法,具体说明了化学动力学纳米颗粒在癌症治疗中的作用、低维纳米材料的应用以及新出现的抗耐药性策略。此外,它还探索了放射治疗、光疗方式和用于诊断和治疗的生物工程病毒样纳米粒子中的纳米技术。最后一节回顾了纳米治疗的临床应用和前景,考察了纳米药物的临床转化以及癌症纳米治疗的当前局限性。它还探讨了纳米粒子应用的未来方向,并研究了遗传毒性、免疫毒性、细胞毒性评估、安全性特征、靶向药物递送及其在病毒致癌中的作用。这本书是肿瘤学和纳米技术领域的研究人员、临床医生和学生的有用资源。本站不对文件进行储存,仅提供文件链接,请自行下载,本站不对文件内容负责,请自行判断文件是否安全,如发现文件有侵权行为,请联系管理员删除。
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