激光触发的纳米生物材料用于抑制肿瘤生长

English | PDF EPUB (True) | 2024 | 251 Pages | ISBN : 9819742196 | 126.2 MB

This book focuses on laser-triggered nanobiomaterials for tumor inhibition. In this book, magnetic iron oxide nanoparticle-mediated cancer PTT through intratumoral or/and intravenous injection is introduced first. The benefits of intratumoral injection and the main factors affecting the retention of materials and permeability in solid tumors have been discussed. Furthermore, an attempt has been made to explore the performance of magnetic iron oxide nanoparticles after intravenous injection for tumor-targeted PTT based on several strategies. The latter part probes the gaps to improve magnetic iron oxide nanoparticle-mediated PTT through intratumoral and intravenous injection modes. This book also includes discussion on drug-loaded magnetic nanocomposites, magnetic iron oxide/Au nanocomposites, and magnetic iron oxide/semiconductor nanocrystal nanocomposites for combination cancer therapy, and enhanced cancer PTT has also been included as an integral part. This book also summarizes the most investigated photothermal agents, including noble metal nanoparticles, especially gold nanostars, hollow mesoporous copper sulfide nanoparticles, carbon-based nanoparticles, especially carbon nanotubes and graphic carbon nanocages, black phosphorous nanosheets, conjugated polymer nanoparticles, and organic dye nanoparticles. This book is useful for undergraduate and postgraduate students to better understand this research area. It may also provide useful information for technical nonspecialists whose background is in nanoscience and nanotechnology, biology, medicine, pharmacy, materials, chemistry, and physics.

这本书专注于激光触发的纳米生物材料用于肿瘤抑制。在这本书中，首先介绍了磁性氧化铁 nanoparticle 通过瘤内或静脉注射介导的癌症 PTT 的机制。讨论了瘤内注射的好处以及影响固体肿瘤中的材料保留和渗透的主要因素。此外，尝试探索了基于几种策略的静脉注射后磁性氧化铁 nanoparticle 对肿瘤定向PTT 性能的表现。本书后面部分探讨了通过瘤内和静脉注射模式改善磁性氧化铁 nanoparticle 介导的 PTT 的缝隙问题。这本书也包括药物负载的磁纳米复合材料、磁性氧化铁/金纳米复合材料以及磁性氧化铁/半导体纳米晶纳米复合材料用于组合癌症治疗，并且增强的癌症PTT也被视为一个组成部分。这本书还总结了最有研究的光热剂，包括贵金属 nanoparticle，尤其是金星形 nanoparticle，空心介孔铜硫化物 nanoparticle，碳基 nanoparticle，特别是碳纳米管和石墨烯纳米笼，黑磷纳米片，共轭聚合物 nanoparticle 和有机染料 nanoparticle。 这本书对本科生和研究生更好地理解这一研究领域很有帮助。它也可能为背景是纳米科学和技术、生物学、医学、药学、材料学、化学和物理学的技术非专家提供有用的信息。

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