GABAA受体，第二版

English | PDF EPUB (True) | 2024 | 349 Pages | ISBN : 3031671473 | 45.2 MB

This new edition presents an up-to-date, comprehensive overview of the GABAB receptor system, including a particular focus on the most recent therapeutic applications and potential. This receptor system has been implicated in several diseases and disorders, including gastroesophageal reflux disease, epilepsy, mood disorders, depression, and alcohol and substance use disorder. The authors, leading researchers in the field, explore a number of approaches, including medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology. The new edition is completely reworked and updated, featuring the latest pharmacological advances on baclofen and positive allosteric modulators.

这一新版呈现了一个最新的、全面的GABAA受体系统概述，特别关注了最近的治疗应用和潜在性。这一受体系统在包括胃食管反流病、癫痫、情绪障碍、抑郁以及酒精和物质使用障碍在内的多种疾病和紊乱中已被证明与之相关。作为该领域的研究者，作者们探讨了许多方法，包括药化化学、分子生物学、生理学以及临床前及临床的药物药理学。这一新版完全重新编写并更新，包含最新的药理学进展如巴氯芬和正向配体调节剂的最新发现。

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