神经外科进展与技术标准：第53卷

English | PDF EPUB (True) | 2024 | 235 Pages | ISBN : 3031670760 | 109.6 MB

This book presents a comprehensive update on some crucial aspects of brain and spinal tumoral pathology that strongly influence the current surgical management. It covers a range of topics, from the latest results of molecular diagnosis for tumors still considered unsuitable for surgical excision, to the increasing use of minimally invasive approaches made possible by the wide application of neuroendoscopic techniques. The first three chapters discuss basic research on the potential benefits of new, less invasive and more sophisticated techniques for brain exploration. The following four chapters examine how modern instruments for intraoperative visualization are modifying the traditional paradigm of classical neurosurgery. Two chapters describe he recent understanding of two of the most relevant intracranial tumors that still pose challenges for successful treatment, namely the tumor of the pineal region and ependymomas. Two more chapters are devoted to the management of brain tumors, the first exploring the valuable information that can be derived from biopsy when properly carried out, and the second detailing an innovative therapeutic modality that increases the intratumoral level of antineoplastic agents while minimizing body toxicity and side effects. The book also delves into congenital or acquired malformations of the brain, the skull base, and the cranial vault in three of its remaining chapters. Finally, the last chapter addresses the traumatic pathology of the spine, whose etiology and management have changed significantly in recent years.

这本书全面更新了一些对当前外科管理至关重要的大脑和脊髓肿瘤病理学的方面。它涵盖了从目前仍不适用于手术切除的肿瘤的最新分子诊断结果，到得益于神经内镜技术广泛使用而得以增加的微创方法的应用范围。 第一至第三章讨论了脑探索的新、更温和且更为先进的技术可能带来的潜在好处的基础研究。接下来的四章则审视现代术中可视化仪器如何在传统经典神经外科的传统范式下进行修改。两章描述了关于目前仍对成功的治疗构成挑战的两种最相关的颅内肿瘤的理解，即松果体区肿瘤和室管膜瘤。另外两章关注脑肿瘤管理，第一章探讨当正确实施时可以从活检中获得的重要信息，第二章则详述了一种增加肿瘤内部抗肿瘤药物水平并尽可能减少身体毒性及副作用的创新疗法。 此外，这本书在最后三章中还涉及了大脑、颅底和颅骨内生畸形。最后的一章讨论了脊髓创伤病的病理学，其病因和管理在过去几年中发生了显著变化。

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