《皮肤和毛发异常的鼠突变手册：动物模型与 biomedical 工具》

English | 1994 | pages: 559 | ISBN: 0849383722 | PDF | 58,3 mb

Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.

《皮肤和毛发异常突变小鼠手册》包含48种可供生物医学界使用的突变小鼠，所有这些突变小鼠都与皮肤病相关。该书中详细介绍了很多具有皮肤病的小鼠突变类型，并且通过插图进行了详细的说明。这本书提供了一个单一的来源，帮助您在选择作为复杂研究项目中高级工具的小鼠突变时确定最佳方案。 此外，该书还包括关于家养动物遗传性皮肤病的内容，以供没有小鼠模型或需要补充现有小鼠模型的选择替代。由知名专家撰写的一章详细比较了人类皮肤和小鼠皮肤发育以及使用动物模型、哺乳动物基因组学、角蛋白生物化学、表皮和毛囊周期与动力学、细胞因子和生长因子、角质细胞培养系统、皮肤癌发生、皮肤免疫系统，以及因内分泌系统突变而引起的皮肤变化。 这本书。

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