探索癌症中的肠道微生物组：从生物标志物到个性化疗法

English | 2024 | ISBN: 9781032706450 | 263 pages | True PDF,EPUB | 66.58 MB

This book explores the relationship between the gut microbiome and cancer, illuminating various facets from fundamental roles to personalized therapies. It provides a comprehensive overview of the impact of the gut microbiome on cancer development, offering potential for innovative diagnostic and treatment approaches.

The book discusses the role of dysbiosis in cancer development, the influence of the microbiome on treatment responses, and strategies to modulate the microbiome for enhanced therapies. It reviews the influence of the gut microbiome on immunotherapy resistance and chemoresistance in cancer patients. Additionally, the book presents gut microbiome biomarkers for cancer diagnosis and prognosis, the implication of the gut-brain axis on cancer development and progression, and the impact of diet and lifestyle on the microbiome. Towards the end, the book investigates the role of the gut microbiome in pediatric cancer and provides an outlook on the future challenges, technological advancements, and ethical considerations of gut microbiome research in the context of personalized cancer therapies. This book is intended for cancer researchers, medical oncologists, clinicians, pharmacologists, translational investigators, and medical students.

这本书探讨了肠道微生物组与癌症的关系，揭示了从基础作用到个性化治疗的各个方面的内容。它提供了肠道微生物组对癌症发展的影响概述，并提出了创新诊断和治疗方法的可能性。 书中讨论了菌群失调在癌症发展中的作用、微生物组对治疗反应的影响以及调节微生物组以提高治疗效果的方法。 此外，本书还介绍了用于癌症诊断和预后的肠道微生物组生物标志物，分析了肠脑轴在癌症发展中和进展中的意义，并探讨了饮食和生活方式对微生物组的影响。 书的最后部分调查了肠道微生物组在儿童癌症中的作用，并展望了未来面临的挑战、技术和伦理考量，在个性化癌症治疗背景下研究肠道微生物组的研究。这本书旨在供癌症研究人员、肿瘤学家、临床医生、药理学专家、转化研究员及医学院学生阅读。

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