自闭症谱系障碍：理解女性表型

English | 2024 | ISBN: 3031620712 | 221 pages | True EPUB PDF | 8.6 MB

This book provides a comprehensive overview of the current state of knowledge on autism in females, in order to help understand and clarify gender implications in the autistic female phenotype. Despite the reported higher risk of developing autism in males than in females, few studies have investigated the gender differences at the clinical and neurobiological level. Possible genetic protective factors, as well as differing neurobiological brain trajectories, could be responsible for the male/female discrepancy in prevalence rates (4:1). Moreover, a different clinical phenotype regarding the onset of symptoms, behavioral features and social motivation often skews diagnosis in women. Specifically, the phenomenon of camouflaging or hiding symptoms in high functioning females, due to behavioral coping strategies, contributes to incorrect or delayed diagnosis.

这本书提供了对女性中当前自闭症状态知识的全面概述，目的是为了帮助理解和澄清在自闭症女性表型中的性别影响。尽管有报告称男性比女性更容易患上自闭症，但很少有研究在临床和神经生物学层面上探讨了这种差异。可能的遗传保护因素以及不同的神经生物学大脑发展轨迹可能对男女性别比率差异（4:1）负责。此外，在症状出现的时间、行为特征和社会动机方面的不同临床表型往往会导致女性诊断的偏差。具体来说，由于行为应对策略而导致的高功能女性隐藏或掩饰症状的现象有助于导致误诊或延迟诊断。

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