低剂量率放疗和立体定向放射治疗(第二版)
This new edition summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radiation treatments that are given over a shorter time period compared to conventional radiation fraction sizes, is used to treat a variety of cancers, including prostate, breast, lung, and colorectal. Conventional radiation therapy and hypofractionated radiation therapy often have different effectiveness rates for cancer treatment and have different impacts on normal tissues in terms of causing toxicity. There is a significant and continually evolving body of literature on the use of different dosing regimens to treat a variety of cancers, and radiation oncologists need to keep up with the various dosing schedules, the effect of each regimen on cancer control in different cancers, and how the different schedules affect each organ in terms of toxicity.
这一新版以一种临床易于获取的方式总结了低分割放疗和立体定向放疗的数据和技术。低分割放疗是一种采用疗程时间较短但剂量更大的治疗癌症的方法,适用于前列腺、乳腺、肺癌及结肠癌等多种癌症的治疗。常规放疗与低分割放疗在癌症治疗的效果上往往存在差异,并且对正常组织造成毒性反应的程度也不相同。目前关于不同给药方案用于多种癌症治疗的研究文献量巨大且不断更新发展,因此放射肿瘤学家需要关注各种给药时间表、每种方案对抗癌控制的不同效果以及这些时间表对各个器官所引起毒性的影响。
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