乳腺癌遗传学、免疫学和免疫疗法：一种跨学科的方法

English | 2024 | ISBN-10: 3031658078 | 446 pages| Epub PDF (True) | 22 MB

Genetics have a role in the presence of breast cancer, while the potential role of the immune system leads to consideration of immunotherapy in the treatment of the disease, particularly in metastatic triple-negative breast cancer. The sixth volume of the “Interdisciplinary Cancer Research” series, entitled “Breast Cancer Genetics, Immunology, and Immunotherapy: An Interdisciplinary Approach” publishes comprehensive volumes on immune and genetic mechanisms of breast cancer diagnosis and prognosis. The role of molecular genetics, interleukins, chemokine receptor, and tumor-infiltrated lymphocytes-TILS in breast cancer are explained. Targeting myeloid determinants, SiRNA loaded in drug delivery nanosystems, nucleic acid and drug dual agent nanoplatforms, and oncolytic virotherapy are also discussed in the treatment of breast cancer, particularly in multidrug resistant and metastatic breast cancer. This interdisciplinary series is of special value to researchers working on immunology, genetics, and practitioners working on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value to researchers, oncologists, geneticists, and immunologists who wish to extend their knowledge on breast cancer.

遗传在乳腺癌的存在中起作用，而免疫系统的作用则促使考虑对这种疾病的治疗可能包括免疫疗法，尤其是在转移性三阴性乳腺癌的治疗中。 “跨学科癌症研究”系列丛书第六卷名为《乳腺癌遗传学、免疫学与免疫疗法：一种跨学科方法》，出版了关于乳腺癌诊断和预后的免疫和遗传机制的综合卷。文章解释了分子遗传学、白细胞介素、 chemokine 受体以及肿瘤浸润淋巴细胞（TILS）在乳腺癌中的作用。书中还讨论了针对髓系决定因素的策略，包括使用药物递送纳米系统装载的小干扰RNA、核酸和药物双剂纳米平台，以及利用病毒疗法治疗乳腺癌，尤其是对多药耐药性和转移性乳腺癌患者。这一跨学科系列丛书对于致力于免疫学、遗传学的研究人员和致力于肿瘤学实践者来说都具有特殊价值。这是癌症免疫研究项目（CIP）的一部分，后者是阿里巴巴科学教育与研究中心（USERN）的组成部分。这本书对希望扩展对乳腺癌了解的研究人员、肿瘤学家、遗传学家和免疫学家尤其有价值。

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