Feldman和Pike的《维生素D：第一卷 生物化学、生理学和诊断》第五版

2024 | ISBN: 0323913865 | English | 1232 pages | True PDF | 30 MB

Vitamin D deficiency is a worldwide problem linked to numerous diseases affecting men, women, and children of all ages. Enormous progress in the study of vitamin D has been made since the first edition of this highly-acclaimed book was published nearly 20 years ago, and current research continues to draw headlines. Feldman and Pike’s Vitamin D, Fifth Edition continues to build on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. The two comprehensive volumes provide investigators, clinicians, and students with a comprehensive, definitive, and up-to-date compendium of the diverse scientific and clinical aspects of vitamin D, where each area is covered by both basic and clinical experts in the field.

In Volume I: Biochemistry, Physiology and Diagnostics, international experts in endocrinology, bone biology, and human physiology take readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multi-faceted actions of vitamin D relating both to skeletal and extra-skeletal action. Researchers from all areas of vitamin D will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic, proteomic and metabolomic insights into the mechanisms of disease.

Volume II: Health, Disease and Therapy authoritatively covers the evidence for new roles of vitamin D, ranging from organ transplantation to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. The coverage is appropriately broad, drawing on aspects of internal medicine, pediatrics, nutrition, orthopedics, oncology, neurology, obstetrics and gynecology, and immunology, as well as, new areas for vitamin D including liver metabolism, veterinary medicine and ICU care – including COVID-19. Clinical researchers will gain a strong understanding of the molecular basis for a particular disease and better understand future directions for research in this still-growing field.

A comprehensive reference ranging from basic biochemistry, cell biology, and physiology principles to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientificand clinical aspects of vitamin D, as opposed to searching through thousands of journal articles Chapters written by the most prominent and well-published names in the field

维生素D缺乏是一个影响男女老幼的全球性问题，与多种疾病有关。自近二十年前首版这部备受推崇的书籍出版以来，关于维生素D的研究取得了巨大的进展，当前的研究仍在引起关注。Feldman和Pike所著的《维生素D 第五版》继续沿用了以往版本的成功模式，从基础研究出发，逐步深入到治疗学领域的最前沿概念。这两卷内容全面、权威且最新的综合文献为研究人员、临床医生和学生提供了关于维生素D的多样科学与临床方面的详尽综述，在每个领域都由该领域的基本和临床专家撰写。 在第一卷：生化、生理学及诊断中，内分泌学、骨骼生物学和人体生理学领域的国际专家带领读者深入了解维生素D的基本研究。这一杰出的参考书详细回顾了维生素D多方面作用的相关机制，既包括对骨骼的作用，也涵盖其超出骨骼的效应。来自维生素D各个领域的研究人员将能够了解临床观察与实践如何反馈到研究循环中，并因此获得更深入的基因组学、蛋白质组学和代谢组学视角以揭示疾病机制。 第二卷：健康、疾病及疗法权威地涵盖了维生素D新角色的证据，涵盖从器官移植至癌症、糖尿病、炎症性肠病、多发性硬化症、肾病等领域的广泛内容。该覆盖范围恰到好处，整合了内科学、儿科、营养学、骨科、肿瘤学、神经学、妇产科和免疫学等方面，并特别包括维生素D的肝脏代谢、兽医医学以及ICU护理（包括COVID-19）。临床研究人员将能够深刻理解某种疾病的基础分子机制并更好地了解该领域仍在增长中的研究方向。 一本从基本生化原理、细胞生物学及生理原则到维生素D临床诊断和管理影响的全面参考书，帮助研究人员和临床医生快速获取多样科学与临床方面的最新细节，而非需浏览数千篇期刊文章。本版由该领域最显赫且出版量最大的专家撰写的章节。

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