癌症诊断与治疗的分子生物标志物

English | 31 July 2024 | ISBN-10: 9819937450 | 781 pages| Epub PDF (True) | 57 MB

This book presents recent advancements, challenges, and clinical implications of molecular biomarkers in various cancers. This book highlights the clinical applications of biomarkers are extensive for cancer risk assessment, screening and early detection of cancer, accurate diagnosis, patient prognosis, prediction of response to therapy, and cancer surveillance and monitoring response. It also explores the progress of predictive biomarkers as an adjunctive tool to tumor immunotherapy in effectively identifying the efficacy of immune checkpoint inhibitors and discusses their future directions in achieving precision immuno-oncology. Further, the book examines the combination of next-generation sequencing and advanced computational data analysis approaches in the understanding of the genomic underpinnings of cancer development and progression. Towards the end, the chapter discusses the role of some commonly investigated phytochemicals and their epigenetic targets that are of particularinterest in cancer prevention and cancer therapy. It is a must for researchers as well as advanced students and physicians in the field of cancer and clinical oncologists.

这本书介绍了各种癌症中分子标志物的最近进展、挑战和临床意义。本书强调了生物标志物在癌症风险评估、癌症筛查及早期检测、准确诊断、患者预后预测、治疗反应预测以及癌症监测等方面的应用广泛性。此外，还探讨了作为肿瘤免疫疗法辅助工具的预测性生物标志物的发展进程，并讨论了它们实现精准免疫治疗的未来方向。本书还研究了下一代测序与先进的计算数据分析方法在理解癌症发展和进展的基因组基础方面的结合。最后，章节讨论了一些经常被研究的植物化学物质及其在癌症预防及癌症治疗中的表观遗传目标的作用。这本书对癌症领域以及临床肿瘤学家的研究人员、高级学生和医生来说都是必不可少的。

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