植物化学物质在脑老化中的神经保护作用

English | 2024 | ISBN-10: 981997268X | 398 pages| Epub PDF (True) | 25 MB

This book discusses the mechanism and therapeutic strategies of phytochemicals against brain ageing. It discusses the underlying anti-oxidative and anti-inflammatory mechanisms of the phytochemicals and the implications of these compounds in the prevention and treatment of geriatric diseases. It discusses the potential role of the highly complex interactive network between the gut and the brain in neurodegenerative diseases such as Parkinson’s disease (PD), and Alzheimer’s disease. The chapters provide insight into the mechanisms involved in brain ageing and the mechanism of actions of the phytochemicals that might be crucial in developing effective new therapies against brain ageing. The chapter also presents the mechanisms of action of phytoconstituents, bioavailabilities, and their effects on neuroinflammation. The chapters also examine the phytochemicals protection of neurons via targeting oxidative stress, mitochondrial dysfunction, neurotrophic factor deficit, apoptosis, and abnormal protein accumulation. This book aims to provide comprehensive and cutting-edge information on the potential neuroprotective role of phytochemicals on the brain and neurological disorders to researchers, neuroscientists, clinical nutritionists, and physicians.

这本书讨论了植物化学物质对抗脑衰老的机制和治疗策略。它探讨了植物化学物质背后的抗氧化和抗炎机制，以及这些化合物在预防和治疗老年疾病中的潜在作用。它还探讨了肠道与大脑之间高度复杂互动网络在如帕金森病（PD）和阿尔茨海默病等神经退行性疾病中可能的角色。章节提供了脑衰老过程中涉及的机制及其植物化学物质作用机制的关键信息，这可能是开发针对脑衰老的有效新疗法的关键所在。章节还概述了植物次生代谢物的作用机制、生物利用度以及它们对神经炎症的影响。此外，章节还探讨了通过靶向氧化应激、线粒体功能障碍、神经营养因子缺乏、凋亡和异常蛋白质积累来保护神经元的植物化学物质的作用机制。这本书旨在为研究人员、神经科学家、临床营养学家和医生提供关于植物化学物质在大脑及神经系统疾病中的潜在神经保护作用的全面且前沿的信息。

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