《致命的遗产：一场家族不幸揭露了一桩 deadly 医学谜团》[有声书]

Weaving his own moving family story with a sweeping history of cancer research, Lawrence Ingrassia delivers an intimate, gripping tale that sits at the intersection of memoir and medical thriller. Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come—to present day, as Ingrassia and countless others continue to unpack and build upon Li and Fraumeni’s initial discoveries, and to understand what this means for their families. In the face of seemingly unbearable loss, Ingrassia holds onto hope. He urges us to “fight like Charlie,” his nephew who battled cancer his entire life starting with a rare tumor in his cheek at the age of two—and to look toward the future, as gene sequencing, screening protocols, CRISPR gene editing, and other developing technologies may continue to extend lifespans and perhaps, one day, even offer cures.

以癌症研究的宏大历史为基础，劳伦斯·因格拉斯用自己独特的家庭故事编织了一部引人入胜的自传体小说。因格拉斯失去了他的母亲、两个姐妹、兄弟和一个侄子，他们都死于不同的癌症，这些癌症在他们的一生中不同时期发展出来。尽管这种情况并不常见，但他的家庭也不停地质疑，他们的悲痛是否只是无法想象的不幸，还是可能存在其他解释。

通过细致的研究和扣人心弦的故事叙述，《因格拉斯》带领我们从1960年代——当时弗雷德里克·彼洛斯博士与约瑟夫·法兰尼二世博士首次相遇，但他们还不知道他们会做出开创性发现，并影响癌症患者数十年之久——直到今天。《因格拉斯》与无数其他人一起继续解开并建立在里和法兰尼的最初发现之上，并了解这对我们家庭意味着什么。

面对看似无法承受的失去，《因格拉斯》中充满希望。他鼓励我们要像他的侄子查理一样“战斗”，后者一生都在与癌症作斗争，从两岁时脸上的罕见肿瘤开始——并展望未来，基因测序、筛查程序、CRISPR基因编辑以及其他发展中的技术或许将继续延长寿命，并有可能在未来甚至治愈疾病。

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