《激活与解毒酶：功能及其 implications（第二版）》

English | 2024 | ISBN: 3031552865 | 272 Pages | PDF EPUB (True) | 8 MB

This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry. The book will also be valuable to advanced researchers. The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers. This new edition is updated throughout andfeatures completely new chapters on Oxidative and Electrophilic Stresses, Metabolite- Mediated Disease Conditions, and Defense Mechanism: Nrf2-ARE Pathway.

这本书讨论了激活和解毒酶的功能及其影响的许多进步。组织精炼、简洁的概述将满足初涉此重要主题者的需求，特别是生物医学科学、生物化学、营养学、药理学和化学领域的学生和研究人员。这本书也将对高级研究者有帮助。本书重点介绍了外源化合物代谢酶领域相关主题，包括生化方面，例如脂溶性外源化合物、激活与解毒酶、代谢酶催化性质、活性代谢中间体、生物医学和生化效果、遗传多态性、酶诱导性、酶调控以求健康益处、膳食相关的酶调节剂以及酶诱导物的结构特征。此新版在各个部分都进行了更新，并包含完全新的章节，内容涉及氧化和电负性应激、代谢产物介导的疾病条件及防御机制：Nrf2-ARE途径。

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