系统医学的概念基础

English | 2024 | ISBN: 9798891134959 | 306 pages | True PDF | 25.08 MB

As the twenty-first century unfolds, medicine is facing several significant challenges that threaten to cripple its advancement and practice. One of the responses to these challenges is the emergence of systems medicine, and one of the more pertinent challenges is identifying and clarifying systems medicine’s conceptual and theoretical foundations. This book represents a sustained effort to examine this challenge and to map the terrain by which to engage it and to pursue possible solutions. This conceptual and theoretical challenge in particular needs to be addressed to ensure the future success of systems medicine. To that end the book explores the conceptual and theoretical foundations of systems medicine, including the major concepts of organicism, emergence, and robustness, and contrasts these concepts with those of biomedicine, including mechanism, resultant, and homeostasis. Moreover, this challenge is critical because its resolution provides the intellectual scaffolding necessary for structuring the concepts and theories required to understand and explain more adequately or completely biological, physiological, and pathological mechanisms and processes. Importantly, with a robust conceptual and theoretical scaffolding, systems medicine must be implemented interdisciplinarily, not only within the medical community, but also within the social and political communities, which the COVID-19 pandemic made so painfully obvious.

在二十一世纪展开之际，医学面临着几项重大的挑战，这些挑战威胁着其进步和实践。对这些挑战的回应之一就是系统医学的出现，而其中一个更加相关的挑战在于识别并澄清系统医学的概念与理论基础。本书代表了持续的努力来检视这一挑战，并通过了解这一领域来应对它，并寻求可能的解决方案。尤其是这种概念与理论上的挑战需要被解决，以确保系统医学未来的成功。为此，本书探讨了系统医学的概念和理论基础，包括有机主义、涌现以及稳健性等主要概念，并将其与生物医学中的机制、结果和稳态对比。此外，这一挑战至关重要，因为它所提供的牢固的概念与理论基础是构建理解并更完善地解释生物学、生理学和病理学机制和过程所需的概念与理论的关键所在。重要的是，在拥有了一个稳固的概念和理论框架后，系统医学必须跨学科进行实施——不仅在医疗界内部，也在社会和政治界内，这在新冠疫情的冲击下变得异常明显。

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