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基于外泌体的药物递送策略用于脑部疾病

English | 2024 | ISBN: 981998372X | 467 Pages | PDF EPUB (True) | 51 MB

This book provides a comprehensive overview of the role of exosomes in brain diseases, including stroke, multiple sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and depression. It covers the basics of exosome biogenesis, composition, and synthesis, as well as the therapeutic potential of exosomes in brain disorders. The correlation between exosomes and neuroinflammation, the challenges of using exosomes as a novel carrier, and engineered exosomes to deliver therapeutic protein are covered well in this book. Use of radiolabelled exosomes as a diagnostic tool and the toxicity studies of exosomes with potential overcome approaches. It is an essential resource for researchers, clinicians, and healthcare professionals working in the field of exosome research, especially on its applications in brain disorders.


这本书提供了外泌体在脑疾病中的作用的全面概述,包括中风、多发性硬化症、帕金森病、阿尔兹海默病、癫痫和抑郁。它涵盖了外泌体起源的基本知识、组成和合成,以及在外科疾病方面的外泌体治疗潜力。书中详细介绍了外泌体与神经炎症之间的关系,使用外泌体作为新型载体的挑战,以及通过工程化外泌体递送治疗蛋白的情况。此外,书中还讨论了放射标记外泌体作为一种诊断工具的应用,以及潜在克服的外泌体毒性的研究。这本书对从事外泌体研究领域尤其是脑疾病应用的研究人员、临床医生和医疗保健专业人员来说是一个必不可少的重要资源。
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