心脏淀粉样变性:诊断与治疗
Cardiac amyloidosis (CA) is caused by the accumulation of amyloid fibrils in the extracellular space of the myocardium, with clinical manifestations including conduction disturbances and heart failure. CA has traditionally been considered a rare disease, lacking effective therapies and with a poor prognosis, but in recent years, increased possibilities for non-invasive diagnosis and greater awareness of the disease have led to the identification of a growing number of cases, challenging the concept of CA as a rare disease. This is why the ability to recognise and manage patients with CA should become part of the core curriculum of cardiologists, but also of internal medicine specialists, general practitioners, neurologists, nephrologists and haematologists. This book, written by leading experts in the field, will provide the state-of-the-art in the diagnosis and management of CA and will also discuss the latest research developments and future research directions.
心脏淀粉样变性(CA)是由于心肌外在细胞间隙中积累了淀粉样纤维所致,临床表现为传导障碍和心脏病。CA长期以来被认为是一种罕见疾病,缺乏有效的治疗方法且预后不佳,但近年来非侵入性诊断的可能性增加以及对疾病的认识提升,导致越来越多的病例被识别出来,挑战了CA为一种罕见病的概念。这就是为什么能够识别并管理CA的能力应该成为心脏科医生的核心课程的一部分,同样也是内科专家、全科医生、神经科医生、肾病科医生和血液科医生的核心内容。由该领域顶级专家撰写的这本书将提供CA诊断和管理的最新水平,并讨论最新的研究进展以及未来的研究方向。
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