近期关于药用植物的研究进展,第40卷:黄酮类和抗氧化剂
Flavonoids are natural anti-oxidants derived from plants with the ability to sequester free radicals. Antioxidants are molecule that inhibit oxidation and harmful activities of free radicals. Natural oxidants are phytochemicals in the form of secondary metabolites that acts as reducing agents, hydrogen donators and single oxygen quenches. Thus, flavonoids may play a significant role in the decreased risk of chronic disease associated with a diet rich in plant-derived foods. Flavonoids are also common constituents of plants in traditional medicine to treat a wide range of diseases. The studies on flavonoids in traditional medicine have remarkably increased in the recent years. The volume on "Flavonoids and Antioxidants" of Recent Progress in Medicinal Plants Series explores structural variations of all subclasses of flavonoids, techniques for isolation, purification and determination of structures, chemical synthesis, biosynthesis and genetic, patterns of distribution in plants and uses. Simultaneously, the properties of antioxidants have been presented to understand their mechanisms, to clarify their activities and discussed to emphasize the importance of flavonoids by displaying a wide range of pharmacological and biochemical actions, such as antioxidants, antibacterial, antifungal, antithrombotic, antimutagenic, antiobesity and ant carcinogenetic activities. In brief, this Volume aims to describe those flavonoids and antioxidants, which possess many important bioactivities in a comprehensive and organized manner. The 24 chapters contributed by 77 contributors deals with the recent findings coupled with review related to all above aspects of flavonoids and antioxidants.
黄酮类是来源于植物的天然抗氧化剂,具有捕获自由基的能力。抗氧化剂是一类能够抑制自由基及其有害活性的分子。天然抗氧化剂是一种形式为次级代谢物的植物化学物质,它们以还原剂、供氢体和单电子氧化剂的形式起作用。因此,黄酮类可能在富含植物食物的饮食中扮演着减少慢性疾病风险的重要角色。此外,在传统医学中,黄酮类也是常见成分之一,用于治疗多种疾病。近年来,对传统医学中的黄酮类研究显著增加。《Recent Progress in Medicinal Plants系列》的“黄酮类和抗氧化剂”卷探讨了所有亚类黄酮类化合物的结构变异、分离、纯化和鉴定结构的技术、化学合成、生物合成及植物中分布模式以及它们的应用。同时,还介绍了抗氧化剂的性质来理解其机制、澄清其活性,并通过展示广泛的药理学和生化作用强调了黄酮类的重要性,例如抗氧化剂、抗菌、抗真菌、抗血栓、抗致突变性、抗肥胖及抗癌活性。简而言之,该卷旨在以系统和组织化的形式描述那些具有多种重要生物活性的黄酮类和抗氧化剂。77名作者贡献了其中的24章,涵盖了所有相关方面黄酮类和抗氧化剂的最新发现以及综述内容。
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