神经性疾病中的药物递送策略：挑战与机遇

English | 2024 | ISBN-10: 9819968062 | 469 pages| Epub PDF (True) | 31 MB

This book comprehensively reviews the recent progress in their pathogenesis and management approaches for neurological disorders. It focuses on understanding the molecular mechanism, pathology, novel nanotechnology-based approaches against stroke, Alzheimer’s disease, Parkinson disease, Huntington’s disease, Multiple sclerosis, and Epilepsy. The book provides the basic understanding about the development and progression of these diseases, and recent pharmacotherapeutic approaches for their management. It also discusses challenges in drug development for neurological disorders, including preclinical models of disorders, the need for drugs to cross the blood-brain-barrier, and limited understanding of relevant pathophysiology. The book also focuses on different conventional and novel strategies for drug delivery in neurological disorders. Towards the end, the book reviews the applications of nanotechnology for the diagnosis of neurological disorders. One of the chapters is focused on the role of herbal actives in the treatment of neurological disorders. Finally, a chapter is included on nanotechnology-based approaches for diagnosis of neurological disorders. This book is a useful resource for students and researchers of pharmaceutical sciences, life sciences, material sciences, and nanosciences.

这本书全面回顾了神经系统疾病的病因学和管理方法的最近进展。它侧重于理解分子机制、病理学，以及基于纳米技术对抗中风、阿尔茨海默病、帕金森病、亨廷顿舞蹈症、多发性硬化症和癫痫的新颖方法。本书提供了这些疾病的发展和进展的基本理解，以及它们管理方面的最新药物疗法。同时讨论了神经疾病药物研发中的挑战，包括疾病的前临床模型、需要穿过血脑屏障的药物，以及对相关病理生理学理解有限的问题。此外，这本书还专注于神经系统疾病中不同的传统和新型给药策略。书的最后一章回顾了纳米技术在神经疾病诊断的应用。其中一章关注草本活性成分在治疗神经系统疾病中的作用。最后，有一章专门介绍基于纳米技术的神经疾病诊断方法。这本书对制药科学、生命科学、材料科学以及纳米科学的学生和研究人员来说是一个有用的资源。

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