干细胞和组织工程：骨骼、软骨以及相关关节组织的缺陷

English | 2024 | ISBN: 9781003245353 | 355 pages | True PDF | 63.49 MB

This book covers conventional clinical treatment methods for handling bone, cartilage, and related disorders along with their limitations and highlights the current state of the art of tissue engineering as an alternative for regenerating such defective tissue. Potential biomimetic scaffolding materials and their development, desired properties, modifications, and optimizations are described. The design and advancement in fabrication, characterization, properties, and biological functions of scaffolds, their integration with stem cells, and various bioreactor systems for tissue regeneration are presented. It further reviews in vitro and in vivo (pre-clinical) assessments of tissue constructs, involved translational challenges, and strategies in various stages of neo-tissue production.

Features

Discusses the key aspects of generating engineered bone, cartilage, and associated tissues through tissue engineering approach Describes multiple engineering principles, and processes involved in the various stages of developing biomaterials and scaffolds Covers integration of stem cells with scaffolds, including assessment of tissue grafts, and translational strategy Explores key factors influencing tissue graft generation in bioreactors and challenges involved in various stages Includes several exercises including review questions and numerical problems for better understanding of the subject This book is aimed at researchers, students, and professionals in biomedical engineering, tissue engineering, stem cells, biomaterials, and orthopaedics.

这本书涵盖了处理骨骼、软骨及其他相关疾病的常规临床治疗方法及其局限性，并强调了作为再生缺陷组织替代方案的生物工程学的当前状态。介绍了潜在的仿生支架材料及其实验室研发，描述其所需性质、修改和优化。展示了支架设计与制造的进步、特性分析及生物学功能，以及它们与干细胞结合的情况，还包括用于组织再生的各种生物反应器系统。它还回顾了在体外和体内（前临床）对组织构建的评估，涉及的技术转化挑战及各个生产阶段中的策略。 特点 讨论通过生物工程途径产生人工骨骼、软骨及相关组织的关键方面 描述各种发展阶段中开发生物材料和支架所需的各种工程原理与过程 涵盖了将干细胞整合到支架中的内容，并包括对移植组织的评估以及技术转化策略 探讨了在生物反应器中生成组织的相关因素，以及各个阶段面临的挑战 包含多种练习题，如复习问题和数值问题等以帮助更好地理解该主题 这本书旨在为生物医学工程、再生医学、干细胞、生物材料及骨科研究者、学生和专业人士提供指导。

---

Download from free file storage

 Download from rapidgator.net  Download from nitroflare.com

---

我要反馈

---

本站不对文件进行储存，仅提供文件链接，请自行下载，本站不对文件内容负责，请自行判断文件是否安全，如发现文件有侵权行为，请联系管理员删除。