家族性和遗传性结直肠癌

English | ISBN: 1527587347 | 2022 | 520 pages | PDF | 16 MB

This book describes the historical context of colorectal cancer predisposition syndromes and the latest knowledge relating to each of the known hereditary colorectal cancer predisposition syndromes. There is a particular focus on the management of each of these syndromes in turn, including medical and surgical management, cancer surveillance, and screening recommendations. It also explores the workings of specialised hereditary and familial cancer clinics from the perspectives of the various clinicians involved in the running of the service. Multidisciplinary management, universal tumour screening, risk estimation, the obtaining and use of genetic information, and appropriate high-risk population screening and surveillance are also discussed, as are future developments and how these may relate to this exciting and evolving field.

这本书描述了结直肠癌易感综合征的历史背景以及与之相关的所有已知遗传性结直肠癌易感综合征的最新知识。特别关注每个已知的综合征的管理，包括医疗和手术管理、癌症监测和筛查建议。还从各个参与服务运行的临床医生的角度探讨了特殊遗传性和家族性癌症诊所的工作原理。这本书也讨论了多学科管理、普遍肿瘤筛查、风险评估、获取和使用遗传信息以及针对高风险人群的适当筛查与监测，同时也涉及未来的进展及其可能与这个激动人心且不断发展的领域有关的内容。

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