造血干细胞移植后的长期管理：预防和并发症处理

English | 414 pages | Wiley-Blackwell; 1 edition (December 16, 2013) | 111847340X | PDF | 5.51 Mb

Currently more than 100,000 patients undergo blood and marrow transplantation (BMT) annually worldwide, a number which is steadily increasing. Long-term survival after BMT has improved significantly since its inception over 40 years ago, due to improved supportive care and early recognition of long-term complications. With broadening indications, more options for BMT, and improvement in survival, by 2020 there may be up to a million long-term survivors after BMT globally.

Higher than average rates of second malignancies and cardiopulmonary, infectious, endocrine, and renal diseases, and bone loss or avascular necrosis amongst this population suggest that the rapidly swelling ranks of BMT survivors require more frequent screening and earlier interventions than the general population.

The purpose of Blood and Marrow Transplantation Long-Term Management is to describe practical approaches to screening for and managing these late effects, with the goal of reducing preventable morbidity and mortality associated with BMT.

This unique new book is the first to address the needs of the increasing population of long-term survivors after stem cell transplantation, making it a must-have resource for all oncologists, hematologists, and primary care physicians involved in the long-term management and care of BMT patients.

目前全球每年有超过10万名患者接受骨髓和造血干细胞移植（BMT），这一数字正在稳步增长。自40多年前BMT诞生以来，由于支持性护理的改进和早期识别长期并发症，患者的长期生存率已有显著提高。随着适应症的扩大、更多的BMT选择以及生存率的提升，在2020年全球可能有超过一百万骨髓移植后存活者。 该群体中高于平均水平的第二原发癌发生率及心血管、呼吸系统、内分泌和肾脏疾病，以及骨骼丢失或血管化坏死等问题，表明骨髓移植幸存者的快速增长群体需要比普通人群更频繁的筛查和早期干预。 《骨髓造血干细胞移植长期管理》的目的在于描述用于筛查和管理这些晚期效应的实际方法，以减少BMT相关的可预防病残率和死亡率。 这本书是首个针对增加的自体干细胞移植后长期幸存者的需求而编写的新书，使其成为所有参与BMT患者长期管理和护理的肿瘤学家、血液学家和全科医生不可或缺的资源。

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