《肿瘤学》第1版

2020 | ISBN: 0323549454 | English | 429 pages | True PDF | 37 MB

Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed.

Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy. Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer. Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment. Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care. Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects. Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

慢性肾病和癌症是需要肾内科医生和肿瘤科医生具备专门知识和技能的常见并发症。由这一新兴亚专业领域的先驱共同撰写的《Onco-Nephrology》，提供权威且全面的内容，涵盖了这两种致命疾病的发生机制与管理策略。这本书作为独一无二的单卷资源，涵盖了当前的治疗协议，并推荐了旨在制止肾衰竭并让癌症治疗继续成功的治疗方法。 本书涵盖了从多种癌症发展而来的急性及慢性肾病。这包括由恶性肿瘤直接导致的肾脏损伤、癌症相关性旁路效应以及用于治疗恶性肿瘤的各种药物。 针对癌症患者中与肾病共存的关键问题进行了讨论，其中包括常规化学疗法方案和新型疗法（靶向药物和免疫疗法），这些疗法可能促进或引发肾损伤；因肾病而非癌症引起的慢性肾病患者出现的癌症；以及肾脏移植，这种手术已被证实可能增加患癌风险。 书中有专门章节介绍了每类常规化学疗法、靶向肿瘤治疗药物和癌症免疫疗法的基本科学知识、致伤机制、临床症状以及治疗方法。 本书还为每种化疗药物类别设专章供快速查阅。针对日益复杂的抗癌药物问题，讨论了生存率的提升和需要长期护理的肾病及癌症患者数量增加的问题。 书还包括对抗血管内皮生长因子（anti-VEGF）治疗及其作为免疫疗法的部分章节内容，这些治疗方法因对肾脏副作用而受到关注。 基于ASN核心课程格式构建了一个清晰且逻辑性强的结构，这本参考书籍不仅适用于考核准备，也是日常实践中实用的工具。购买后包含增强版电子书版本，让您可以在多种设备上访问书中的所有文本、插图和引用内容。

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