《胰岛素：一百年历史[Audiobook]》

English | ASIN: B0CTJ7JB9R | 2024 | 8 hours and 19 minutes | M4B@64 kbps | 223 MB

In 1922, researchers made one of the most important medical breakthroughs of the century: insulin. Their discovery seemed miraculous. When it was given to diabetic patients on the brink of death, their condition rapidly improved. However, this was no simple cure. Injections must be taken for life. Without them, symptoms quickly return, often with fatal results. But while a lifetime on insulin poses great challenges, it also offers opportunities. In this revelatory history, Stuart Bradwel looks back on one of medicine's most celebrated innovations. Setting professional narrative against subjective patient experience, he tells the story of a drug that has challenged many of the basic assumptions upon which medical practice is built, both inside and outside the clinic. Nevertheless, Bradwel reminds us that the centenary of this apparent "wonder drug" should be no cause for celebration. Insulin often remains inaccessible to those who need it most: elusive prescriptions, uneven availability and sky-high prices result in rationing and desperate do-it-yourself research and development. In the face of bootstraps rhetoric and "Pharma Bro" capitalists, patients across the world are left to fend for themselves. There is a long way to go in the twenty-first century until insulin truly fulfills the extraordinary promises made by its discovery.

1922年，研究人员做出了本世纪最重要的医疗突破之一：胰岛素。他们的发现似乎奇迹般。当这种药物给即将死亡的糖尿病患者使用时，他们的状况迅速得到改善。然而，这并不是一个简单的治疗方法。必须终生注射。不这样做，症状很快就会回来，有时会导致致命的结果。但是，虽然终身注射胰岛素面临着巨大的挑战，但也带来了机会。在这一令人震惊的历史中，斯图尔特·布兰威尔（Stuart Bradwel）回顾了医学中最著名的创新之一。 他将专业叙事与主观患者体验相结合，讲述了一种药物的故事，它已经对许多构成了基础医疗实践的假设提出了挑战——无论是内还是外的诊所。然而，布兰威尔提醒我们，这个“奇迹药物”百年纪念日不应被视为一场庆祝活动。胰岛素经常对最需要的人失去可及性：难以获得的处方、不均匀的供应和高昂的价格导致了配给和绝望的家庭自制研究与发展。在自力更生的口号和“药商大佬”资本家面前，全世界的患者都不得不自己解决。到了21世纪，直到胰岛素真正实现其发现时所做出的非凡承诺，我们还有很长的路要走。

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