表观遗传学与健康：一本实用指南

English | 2024 | ISBN: 1119307988 | 159 pages | True PDF EPUB | 6.92 MB

Epigenetics and Health

An incisive and contemporary discussion of epigenetic phenomena applied to human health and disease

Epigenetics and Health: A Practical Guide delivers a thorough and insightful exploration of the basic principles of gene function, gene regulation, and gene expression. The author explains how epigenetic modifications alter gene expression and demonstrate the role played by environmental factors―including nutrition, exercise, toxins, and stress―in gene regulation, as well as their potential health consequences.

The book presents current methods for analyzing epigenetic variation, including NGS applications and bioinformatic analysis.

Readers will be encouraged to question, analyze, and critically appraise the literature on epigenetics to further develop their understanding. They’ll also find

Explorations of epigenetic mechanisms, homeostasis, and the potential for manipulating the epigenome Practical discussions of methods for epigenetic analyses How to address cancer epigenetics, mental health epigenetics, and guidance on developing an epigenetics research project

Epigenetics and Health: A Practical Guide will benefit practicing geneticists and medical geneticists seeking insights into epigenetic phenomena applied to human health and disease..

基因表观遗传学与健康 这是一次深刻而当代的讨论，探讨了基因表观遗传现象在人类健康和疾病中的应用。 《基因表观遗传学与健康：一本实用指南》一书深入而详尽地探讨了基因功能、调控机制以及表达的基本原理。作者解释了表观遗传修饰如何改变基因表达，并展示了营养、运动、毒素和压力等环境因素在基因调控中的作用，同时也指出它们可能带来的健康后果。 本书介绍了分析表观遗传变异的当前方法，包括NGS应用和技术及生物信息学分析。 读者将被鼓励质疑、分析并批判性地评估有关表观遗传学的研究文献以进一步加深理解。他们还将发现： - 表观遗传机制、稳态以及操纵基因组潜力的探索 - 对于表观遗传分析方法的实际讨论 - 如何应对癌症表观遗传学、心理健康表观遗传学，以及指导进行表观遗传学研究项目的建议 《基因表观遗传学与健康：一本实用指南》将有助于那些对人类健康和疾病中应用的表观遗传现象感兴趣的临床遗传学家和医学遗传学家。

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