《临床研究 第五版》

Selected as a Doody's Core Title for 2022 and 2023!

For more than 30 years, Designing Clinical Research has set the standard as the most practical, authoritative guide for physicians, nurses, pharmacists, and other practitioners involved in all forms of clinical and public health research. Using a reader-friendly writing style, Drs. Warren S. Browner, Thomas B. Newman, Steven R. Cummings, Deborah G. Grady, Alison J. Huang, Alka M. Kanaya, and Mark J. Pletcher, all of the University of California, San Francisco, provide up-to-date, commonsense approaches to the challenging judgments involved in designing, funding, and implementing a study. This state-of-the-art fifth edition features new figures, tables, and design, as well as new editors, new content, and extensively updated references to keep you current.

Covers clinical research in its many forms, including clinical trials, observational studies, translational science, and patient-oriented research.

Presents epidemiologic terms and principles and advanced conceptual material in a practical and reader-friendly manner.

Discusses key changes in the field, including confounding and directed acyclic graphs, surrogate outcomes and biomarkers, instrumental variables and Mendelian randomization, regression discontinuity designs, alternative data sources, AI and machine learning, pilot studies, as well as an update on P values and Bayesian analysis..

Covers modifications of classic randomized trials, such as pre/post, interrupted time series, difference-in-differences, stepped wedge and cluster randomized designs, as well as randomized trials in health systems.

Adds new chapters on qualitative approaches to clinical research and on community-engaged research

Enrich Your eBook Reading Experience

Read directly on your preferred device(s),such as computer, tablet, or smartphone

Easily convert to audiobook,powering your content with natural language text-to-speech

《设计临床研究》已被选为2022年和2023年的Doody's核心图书！

超过30年来，《设计临床研究》一直作为实践性和权威性的指南，适用于所有形式的临床及公共卫生研究中的医生、护士、药师及其他从业者。由加州大学旧金山分校的Warren S. Browner博士、Thomas B. Newman博士、Steven R. Cummings博士、Deborah G. Grady博士、Alison J. Huang博士、Alka M. Kanaya博士和Mark J. Pletcher博士等提供最新的实用方法，以应对设计、资助及实施研究中的挑战性判断。本书的最新第五版包含了新的图形、表格和设计，以及新编辑、新内容，并通过广泛更新的参考文献来保持您的知识及时更新。

涵盖各种临床研究的形式，包括临床试验、观察性研究、转化科学及面向患者的科研项目。

用实用且易于阅读的方式介绍了流行病学术语和原理，以及高级概念材料。

讨论了领域中的关键变化，如混杂因素与定向有向图、替代结局与生物标志物、工具变量与孟德尔随机化、断点回归设计、替代数据来源、人工智能及机器学习、试点研究等，并更新了关于P值和贝叶斯分析的内容。

介绍了经典随机试验的修改，例如预后/事后的研究、间断时间序列研究、差异-差异研究、楔形设计和集群随机研究，以及在健康系统中的随机试验。

新增了关于临床科研质性方法及社区参与型科研的新章节。

丰富您的电子书阅读体验：

直接读取您偏好的设备上（如电脑、平板或智能手机）

轻松转换为有声书，通过自然语言的文本转语音功能使内容生动起来。

本站不对文件进行储存，仅提供文件链接，请自行下载，本站不对文件内容负责，请自行判断文件是否安全，如发现文件有侵权行为，请联系管理员删除。