体液中的癌症标志物：循环中的生物标志物（PDF）

English | 2017 | ISBN: 3319483595 | 509 Pages | PDF | 6.62 MB

This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.

这本书深入探讨了循环系统中证据、临床应用和潜在癌症标记物，并讨论了循环无细胞核RNA、循环肿瘤DNA、以及表观基因组、基因组、转录组（编码性和非编码性）、蛋白质组（包括传统血清蛋白和蛋白质谱）和代谢组的改变。此外，它还强调了每种癌症类型中循环肿瘤细胞的临床应用，并关注外泌体内容物的重要性，包括微小RNA、致癌基因和耐药因素。因此，它为癌症研究人员、肿瘤学家、医生、外科医生、医学学生、肿瘤学护士、诊断实验室以及制药行业提供了宝贵的参考指南。

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