《毒理学》，第四版

English | 2023 | ISBN: 1032036923 | 317 pages | True PDF | 24.53 MB

As with the previous editions, Introduction to Toxicology, Fourth Edition, continues to chart the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest. For centuries, the study of toxicology has fascinated students. The book begins with basic toxicological principles, including an historical summary, dose-response relationships (NEW chapter), exposure-response relationships (NEW chapter), disposition, and metabolism of xenobiotic toxic substances. Other important new chapters include target organ toxicity, toxicity of carcinogenic agents and new and updated concepts in toxicity testing, and antidotes and treatment of poisonings. In all, nine new or expanded chapters from the third edition are advanced.

Current concerns about the effects of therapeutic drugs, carcinogens, industrial toxins, pesticides, and herbicides on human health, animal welfare, and the stability and maintenance of the ecosystem continue to highlight toxicology as an important and growing scientific discipline.

Key features

Comprehensive coverage of the field of toxicology which illustrates its importance to and impact on society Uses pertinent examples, tables, and diagrams to aid understanding with learning objectives, summaries, questions, and answers for each chapter Clearly and concisely written and presented concepts for easy comprehension by toxicology, biomedical, and health science students Examines the complex interactions associated with toxicological events Covers the effect of toxins on biological and physiological systems

This book successfully condenses the diffuse literature in the field into an accessible and readable text, made easier with the insertion of many tables and figures. It introduces fundamental concepts and builds upon these using topical and relevant historical examples. Its improved format includes learning objectives and summaries of each chapter, as well as questions and answers suitable for self-assessment.

This latest edition is an invaluable resource for undergraduate and graduate toxicology students, as well as an introductory text for other health care students and professionals. The book also functions as a comprehensive introductory reference text for environmental scientists, medical biologists and chemists, chemical engineers, and regulatory agencies, with interests in toxicologically related areas.

正如之前的版本一样，《毒理学导论》第四版继续追踪毒理学领域的演变，从古代部落利用天然毒素的方式，通过帕拉塞尔苏斯所奠定的发展，以及发展到当前公众感兴趣的主题。数百年来，对毒理学的研究一直吸引着学生们的注意。本书从基本的毒理学原理开始，包括历史总结、剂量-效应关系（新增章节）、暴露-效应关系（新增章节），外源性有毒物质的代谢和解毒过程。 其他一些新的重要章节还包括靶器官毒性作用，致癌物毒性作用以及更新的概念在毒性测试中的应用，中毒药物抗毒素及其治疗。总计，在第三版的基础上，有九个新或扩展的新章。 目前对人类健康、动物福利和生态系统稳定性和维护的疗效药物、致癌剂、工业毒物、农药和除草剂的影响持续引起了人们对毒理学的兴趣，使其成为一项重要的、正在增长的科学领域。 关键特点 全面覆盖毒理学领域的所有内容，展示它在社会中的重要性及其影响 使用相关示例、表、图以帮助理解学习目标、总结、问题和答案每个章节 清晰简洁地呈现概念，方便毒理学、生物医学和健康科学学生理解和接受 探讨与有毒事件相关的复杂相互作用 涵盖毒素对生物系统和生理过程的影响 本书成功地将领域内的分散文献浓缩成一个易于阅读的文本，并通过插入许多表格和图表使其更加容易理解。它介绍了基本概念并使用当前的相关历史示例将其构建起来。改进后的格式包括每个章节的学习目标总结以及适合自我评估的问题和答案。 这本书是为本科生和研究生毒理学学生提供的宝贵资源，也是其他健康护理学生及专业人士的入门教材。此外，该书还作为环境科学家、医学生物学家、化学家、化工工程师和对相关毒理学领域感兴趣的监管机构的综合入门参考书籍而发挥作用。

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