宫颈癌:信号通路、分子机制、天然产物和治疗策略
There has been a tremendous advancement in cancer therapeutics, and this book focuses on new approaches to one of the major cancers of the female reproductive system—cervical cancer. Cervical cancer is the fourth most frequent cancer in women worldwide and, especially, a foremost cause of morbidity in women in developing countries, including India. Several research findings have suggested that modulation in various signaling pathways is responsible for cervical cancer pathogenesis, and inhibition of these crucial pathways could be a better therapeutic approach for cervical cancer management. This book expounds on this approach, providing a detailed insight of the deregulated oncogenic signaling pathways involved in the progression of cervical cancer.
The key topics covered within this book include
Signaling pathways involved in cervical cancer Mechanisms behind the involvement of these aberrant signaling pathways Cell signaling pathways and their alterations in cancer Molecular biology behind cervical cancer Drug development approaches for the management of cervical cancer Cervical cancer therapeutics and the possible aspects, including progression and inhibition using natural products and synthetic approaches Oncologists, cancer scientists, and research professionals will benefit from this volume, which provides a single platform that presents new research on the pathways responsible for the progression of cervical cancer so that they, in turn, can design their research work effectively and can discover novel innovations in the field of cancer therapeutics.
癌症治疗方面取得了巨大的进步,本书专注于聚焦女性生殖系统中一种主要癌症——宫颈癌的新方法。宫颈癌是全球妇女中最常见的第四大癌症,在发展中国家尤其是像印度这样的国家,它也是造成妇女患病的主要原因之一。多项研究发现表明,对各种信号通路的调节与宫颈癌的发生有关,而抑制这些关键路径可以成为治疗宫颈癌管理的一种更佳治疗方法。本书就这一方法进行了阐述,并提供了关于参与宫颈癌进展的失调促癌信号通路的详细见解。 本书涵盖的关键话题包括: - 参与宫颈癌的信号通路 - 为何这些异常信号通路会涉及其中 - 癌症中细胞信号通路及其改变 - 宫颈癌背后的分子生物学原理 - 管理宫颈癌的新药开发方法 - 使用天然产品和合成途径治疗宫颈癌以及它们如何促进癌症进展和抑制 癌症学家、癌症科学家及科研专业人士将从本书受益,它提供了一个单一平台,展示负责宫颈癌进展的信号通路的新研究,从而他们可以更有效地设计自己的研究工作,并在抗癌疗法领域发现新的创新成果。
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