环境压力和氧化炎症组织反应（True EPUB）

English | December 15, 2023 | ISBN: 1032357002 | True EPUB | 285 pages | 23.6 MB

Environmental risk factors – noise, air pollution, chemical agents, and ultraviolet radiation – impact human health by contributing to the onset and progression of noncommunicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensive summary of major findings.

This book is a state-of-the-art summary of these myriad severe life stressors. The chapters on the different pollutants focus on disease mechanisms (cardiovascular, neurological and metabolic disorders) and on oxidative stress and inflammation. The editors emphasize emerging mechanisms based on dysregulation of the circadian clock, the microbiome, epigenetic pathways, and cognitive function by environmental stressors, and introduce the exposome concept while highlighting existing research gaps.

Key Features

Links various environmental stressors to the incidence of noncommunicable diseases Includes chapters on airborne toxins, chemical pollutants, noise, and ultraviolet radiation stressors Contributions from an international team of leading researchers Summarizes the impacts of stressors on disease mechanisms

环境风险因素——噪声、空气污染、化学剂和紫外线辐射，通过引发和加速不可治愈疾病的发生和发展影响人类健康。因此，有必要进行临床前及临床研究，并全面总结主要发现。 这本书是对这些众多严重的生活压力的现代综述。各章节专注于不同污染物对疾病机制（心血管、神经系统和代谢紊乱）的影响，以及氧化应激和炎症。编辑强调了基于环境压力调控昼夜节律、微生物组、表观遗传路径和认知功能失常的新机制，并引入暴露谱的概念，同时突出现有研究的不足。 关键特点 将各种环境压力因素与不可治愈疾病的发生率联系起来 包括关于空气中有毒物质、化学污染物、噪声以及紫外线压力的章节 国际顶尖研究人员的贡献 总结了对疾病机制的影响

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