口腔生物利用度和药物递送：从基础到高级概念与应用

English | 2024 | ISBN: 1119660653 | 931 pages | True PDF EPUB | 75.41 MB

ORAL BIOAVAILABILITY AND DRUG DELIVERYImprove the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user's circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. Oral Bioavailability and Drug Delivery readers will also find

口服生物利用度和药物递送，提高新开发并获批药物的性能和生存能力，就需依靠这份至关重要的指南。 生物利用度是衡量药物通过给药方式到达用户循环系统的速度与程度的参数。例如，静脉注射能产生100% 的生物利用度，因为药物直接注入了血液循环系统；然而，在口服给药的情况下，生物利用度可能因多种因素而大相径庭，这些因素如果未得到充分理解，则可能导致药物开发失败、不良反应及其他并发症。因此，口服生物利用度的机制在药物开发中也极为关键。 《口服生物利用度和药物递送》一书提供了这一主题的全面覆盖及其应用于药物开发的详细信息。从基本术语和基本概念入手，它深入探讨了影响因素以及提高生物利用度的可能性。该书的结果是一本不可或缺的研究工具。 《口服生物利用度和药物递送》的读者还将发现

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