铜绿假单胞菌：生物学特性、致病机制及控制策略

English | PDF,EPUB | 2022 | 452 Pages | ISBN : 303108490X | 71.3 MB

This book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions.

This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization.

这本书涵盖了Pseudomonas aeruginosa广泛而规制化的致病因子和防御机制，重点在于其应对压力的反应以及这种机会性人类病原体的进化。 Pseudomonas aeruginosa是导致10%医院感染的原因。此外，这种革兰氏阴性细菌在免疫受损个体中引起持续感染，并且是囊性纤维化患者慢性肺部感染的主要原因。 这本书提供了关于Pseudomonas aeruginosa代谢多样性和其形成的生物膜机制的见解，这些使该微生物成为一种高效的感染媒介。本书邀请读者了解由于多药外排泵、抗生素降解酶和细菌细胞壁渗透性的低度降低而产生的对各种抗微生物剂的内在抵抗能力。特别强调了不同类型分泌系统在致病过程中的进化作用、鞭毛及其在趋化性和表面感知中的角色，以及宿主-病原体相互作用。 这本书对对Pseudomonas aeruginosa生物学和致病性感兴趣的初级科学家来说是一个有用的入门读物。它也为这个领域内工作的高级科学家和医学专家提供了更广阔的视野，超出了他们的专业领域。

---

Download from free file storage

 Download from userupload.net  Download from rapidgator.net  Download from nitroflare.com

---

我要反馈

---

本站不对文件进行储存，仅提供文件链接，请自行下载，本站不对文件内容负责，请自行判断文件是否安全，如发现文件有侵权行为，请联系管理员删除。