胃肠癌的免疫策略

English | 2023 | ISBN: 3031399439 | 534 Pages | PDF EPUB (True) | 11 MB

Immunotherapy has celebrated some astonishing therapeutic successes in a variety of cancer types and is becoming increasingly relevant in daily clinical practice. Currently, the predominant class of immunotherapeutic drugs is the so-called checkpoint inhibitors, which disengage the physiological brakes on the immune system, enabling a more effective anti-cancer immune response. Malignancies of the gastrointestinal tract, which account for the majority of cancer cases worldwide, are a major cause of morbidity and mortality, creating an urgent need for more effective therapies. A large number of clinical trials have evaluated the efficacy of cancer immunotherapy in gastrointestinal malignancies and demonstrated its potential in certain subsets of patients.

免疫疗法在多种癌症类型中取得了惊人的治疗成功，并且正在逐渐成为日常临床实践中越来越重要的部分。目前，免疫疗法的主要类群被称为检查点抑制剂，它们能够解除免疫系统中的生理制动，从而增强更有效的抗肿瘤免疫反应。全球大多数癌症病例都属于消化道恶性肿瘤范畴，这类疾病是导致发病率和死亡率增加的重要原因，因此迫切需要开发更为有效的治疗方法。已经进行了大量的临床试验来评估癌症免疫疗法在消化系统恶性肿瘤中的疗效，并证明了其在某些患者亚群中具有潜力。

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