中枢神经系统病毒和真菌感染
The first section provides the reader with valuable insights into the aetiologies and underlying pathophysiological mechanisms of neurological diseases, including host responses. It mentions all bacterial, fungal, parasitic, and viral causes of neuro-infections, along with rarer neuropathogenesis such as prions and mycoplasmas. The chapter also presents detailed epidemiology and prevalence of different CNS infections worldwide. It also reviews various infectious diseases that target the nervous system, such as focal lesions, meningitis, and neurological complications of venous sinus thrombosis. The next two sections delve deep into pathogen-specific diseases of the CNS, namely the viruses and fungi associated with neuro-infections. It mentions detailed excerpts on encephalitic viruses, long-term consequences of neurotropic viruses, mycological neuroinfectious, and even the emerging, less talked of viruses and fungi causing neurological disease. Topics such as principles of vigorous antifungal therapy and surgeries are also discussed in the chapter. The fourth section gives an insight on prospects for efficiently diagnosing and managing viral and fungal CNS infections, to tackle associated morbidities.
第一部分向读者提供了神经性疾病病因学和潜在病理生理机制的宝贵见解,包括宿主反应。它提到了所有引起神经系统感染的细菌、真菌、寄生虫和病毒原因,以及罕见的神经病理性病变,如朊病毒感染和支原体。该章节还介绍了全球不同中枢神经系统感染的流行病学和患病率。它还回顾了针对神经系统的目标的各种传染病,包括局灶性病变、脑膜炎和静脉窦血栓症引起的神经系统并发症。接下来的两部分深入探讨了与神经系统感染相关的病毒和真菌所引发的具体 CNS 疾病。该章节提到了关于朊病毒性脑炎病毒、神经嗜性病毒的长期后果、真菌性神经系统感染,甚至一些引起神经系统疾病的新兴且不常讨论的病毒和真菌的详细摘录。该章节还讨论了积极抗真菌治疗的原则以及手术的相关话题。最后一部分提供了诊断和管理 CNS 病毒和真菌感染的前景,并应对相关并发症的机会。
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