构建基质金属蛋白酶抑制剂模型

English | 2023 | ISBN: 9781003303282 | 490 pages | True PDF | 161.72 MB

Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more. This book covers various modern molecular modeling methodologies particularly related to MMP inhibitors. Included in the text are descriptions of ligand-based drug designing and structure-based drug designing modeling strategies for designing potential and target specific or selective MMPIs. This book will benefit those who are looking for an in-depth text on the design and discovery processes of novel and selective MMPIs.

Features Describes modeling strategies applied to MMPs Elaborates on the designing strategies of MMPs specifically Includes in-depth analyses of related case studies Acts as a guide for medicinal chemists, not only from pharmaceutical industries, but also from academia Covers various modern molecular modeling methodologies, particularly related to MMPIs

金属蛋白酶（MMPs）已被确立为针对各种癌症、心血管疾病、神经退行性疾病、炎症性疾病等众多重大疾病条件的新药设计和发现中的有前景的生物分子靶标。本书涵盖了与MMP抑制剂相关的多种现代分子建模方法学，特别关注药物设计策略。书中包括了有关MMP的结合基团药物设计和基于结构的设计模型策略的描述，以设计潜在的目标特异性或选择性MMPIs。这本书将对寻求深入了解新型和选择性MMPIs的设计与发现过程的人们有所帮助。

特色 描述了应用于MMP的建模策略 详细介绍了专门针对MMP的药物设计策略 包含深入分析的相关案例研究 作为药剂师的指南，不仅来自制药行业的从业者，也包括学术界的研究人员 涵盖了各种现代分子建模方法学，特别是与MMPIs相关的方法

---

Download from free file storage

 Download from rapidgator.net  Download from nitroflare.com

---

我要反馈

---

本站不对文件进行储存，仅提供文件链接，请自行下载，本站不对文件内容负责，请自行判断文件是否安全，如发现文件有侵权行为，请联系管理员删除。