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癌症表观遗传学(《表观遗传学与人类健康》,第11章)

English | 2023 | ISBN: 303142364X | 730 Pages | PDF EPUB (True) | 19 MB

Epigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns. These changes can lead to alterations involved in tumor formation, imprinting, and metabolic disorders. Recent advances can help us understand the importance of epigenetic changes in both cancer development and tumor progression. In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression.


表观遗传改变是可遗传的变化,在人类发展和组织特异性基因表达模式中扮演着关键角色。这些改变可能导致与肿瘤形成、印记以及代谢紊乱相关的改变。最近的进展有助于我们理解表观遗传变化在癌症发展及肿瘤进展中的重要性。此外,表观遗传学改变也可能成为分析肿瘤进展时有用的诊断和预后标志物。
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