高级临床肾MRI检测方法与协议
This book offers the concepts of quantitative MRI for kidney imaging. Kidney MRI holds incredible promise for making a quantum leap in improving diagnosis and care of patients with a multitude of diseases, by moving beyond the limitations and restrictions of current routine clinical practice. Clinical kidney MRI is advancing with ever increasing rapidity, and yet, it is still not good enough. Several roadblocks still slow the pace of progress, particularly inefficient education of renal MR researchers, and lack of harmonization of approaches that limits the sharing of results among multiple research groups.With the help of this book, we aim to address these limitations, by providing a comprehensive collection of more chapters on MRI methods that serve as a foundational resource for clinical kidney MRI studies. This includes chapters describing the fundamental principles underlying a variety of kidney MRI methods, step-by-step protocols for executing kidney MRI studies, and detailed guides for post-processing and data analysis. This collection serves as a crucial part of a roadmap towards conducting kidney MRI studies in a robust and reproducible way, that promotes the standardization and sharing of data, and ultimately, clinical translation.Chapters are divided into three parts: MRI physics and acquisition protocols, post-processing and data analysis methods, and clinical applications. The first section includes MRI physics background and describe a detailed step by step MRI acquisition protocol. If a clinician would like to perform a renal MRI – this would include the parameters to set up the acquisition on the scanner. By this section, the reader should have the details to be able to successfully collect human renal MR images. In the second section, expert authors describe methods on how to post-process and analyze the data. By this section, the reader should have the details to be able to successfully generate quantitative data from the human renal MR images. In the final section, chapters show clinical examples of various methods. Authors share examples of multi-parametric renal MRI that are being used in clinical practice.This is an ideal guide for clinicians from radiology, nephrology, physiology, clinical scientists, and as well as basic scientists and experts in imaging sciences and physics of kidney MRI. It also provides an opportunity to students, trainees, and post-doctoral fellows to learn about these kidney MRI techniques.
这本书提供了定量MRI的概念,用于肾脏成像。肾脏MRI在改善诊断和治疗患者各种疾病方面具有巨大的潜力,通过超越目前临床实践中现有的限制和限制。临床肾脏MRI正在以惊人的速度进步,但仍然不够好。几个障碍仍在阻碍进展的步伐,特别是肾MR研究者的教育效率低下以及缺乏协调的方法限制了多个研究小组之间结果的共享。希望通过这本书来解决这些问题,提供一个全面收集更多章节的磁共振成像方法作为临床肾脏MRI研究的基础资源。这包括描述各种肾脏MRI方法的基本原理、执行肾脏MRI研究的步骤性规程,以及详细的数据后处理和数据分析指南。这些资料集作为一个关键部分,朝着以稳健且可重复的方式进行肾脏MRI的研究道路前进,推动数据标准化和共享,并最终转化为临床应用。章节分为三部分:MRI物理与获取规程、后处理和数据分析方法及临床应用。第一部分包括磁共振物理学背景以及详细描述的磁共振成像获取规程。如果一个临床医生想要执行肾MRI——这将包括在扫描仪上设置收集参数。通过这一部分,读者应该具有成功采集人类肾脏MR图像所需的细节。第二部分由专家作者描述如何后处理和分析数据的方法。通过这一部分,读者应该能够成功从人类肾脏MR图像中生成定量数据。最后一部分的章节展示各种方法的临床实例。作者分享了多参数肾MRI在临床实践中使用的例子。这是一本理想的指南,适用于放射科、肾病学、生理学、临床科学家以及影像科学和肾脏MRI物理领域的专家。它也为学生、实习者及博士后提供了学习这些肾脏MRI技术的机会。
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