老年患者的药物制剂

English | 2023 | ISBN-10: 3031358104 | 301 pages| PDF (True) | 13 MB

Pharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking.

This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies.

Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.

药品制剂设计影响患者的接受度/依从性和药物的药动学特性。这一点尤其重要，因为老年人由于生理变化和与用药相关的临床和社会情况而存在特别的需求。 这本书提供了一套全面的设计方案来满足老年人群体的需要。书中包括了对影响老年患者药物优化、安全性和接受度的关键临床、社会和制药因素的概述，之后是以患者为中心的考虑，例如监管要求、剂型设计以及人因研究。 高级制药技术被讨论，它们在老年人中的潜在用途，如3D打印、长效口服制剂及新型疫苗技术。本书的独特焦点将对药品科学界内的工业与学术人员寻找更适合老年患者的更好制剂方案具有吸引力。

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