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《肥胖学手册》第1卷:流行病学、病因学和生理病理学,第4版

English | 2023 | ISBN: 9781003437673 | 668 pages | True PDF | 369.16 MB

The fifth edition of Volume 1 of Handbook of Obesity written by global experts covers the basic science aspects under the broad topic areas of epidemiology, etiology, and pathophysiology of obesity. Divided into 5 sections and detailed in 66 chapters, this edition covers the important advances occurring over the past decades. With a focus on science of obesity and factors participating in the etiology of obesity, this topic is studied from biological, behavioural, and environmental perspectives.

Volume 1 is structured into 5 parts Part 1 focuses on the history, definitions, and prevalence of the obesity. It identifies the historical references to excess weight, obesity in art and literature, direct and surrogate measurements of adiposity and obesity related traits, epidemiology of obesity around the globe, and age, sex, and ethnic variation completes this part of the volume. Part 2 explains the biological determinants of obesity. It explains the bioenergetics, energy dissipation mechanisms and exposure to experimental overfeeding, genetic and epigenetic evidence, metabolic rates, energy expenditure and energy partitioning, and the evidence on infections and adiposity. Part 3 describes the behavioral determinants of obesity. It deals with chapters related to food, beverages, and ingestive behavior, dealing with smoking, breast-feeding, and sleep duration and pattern, and sedentary behavior, occupational work, and leisure-time physical activity and obesity. Part 4 comprises of chapters explaining the environmental, social, and cultural determinants of obesity. The chapters in this section focus on the role of agriculture and the food industry in the current obesity epidemic, social and economic aspects of obesity, and ethnic and cultural differences, and environmental pollutants. Part 5 of this volume discusses the health consequences of obesity. The chapters address important topics such obesity and heart disease, lipoprotein metabolism, insulin resistance and diabetes, metabolic syndrome, cancer, hepatic biology, pulmonary functions, and arthritis and gout, mental health and quality of life, growth and health disorders in pediatric populations, and on bias and discrimination affecting the obese persons.


《第五版肥胖手册》的第一卷由全球专家撰写,涵盖了流行病学、病因学和肥胖病理生理学等广泛主题下的基本科学方面。该版本分为5个部分,详细介绍了66章内容,覆盖了过去几十年中发生的重要进展。该话题从生物学、行为学和环境的角度研究肥胖的科学及其参与肥胖发病的因素。 第一卷被分为5个章节。 第一章重点讨论肥胖的历史、定义和流行情况,涵盖对超重历史的引用、艺术与文学中的肥胖现象、身体脂肪测量及肥胖相关特征的直接和间接测量、全球范围内的肥胖流行病学调查、年龄、性别以及种族差异等方面的内容。 第二章解释了导致肥胖的生物学因素。它阐述了能量代谢、能量耗散机制,以及实验性过量饮食暴露下的生物能量过程、遗传证据和表观遗传学证据、新陈代谢率、能量消耗及能量分配情况,以及感染与脂肪堆积的关系。 第三章描述了肥胖的行为决定因素。该部分涉及与食物、饮料和摄食行为有关的章节;探讨吸烟、母乳喂养、睡眠时间和模式,以及久坐行为、职业工作和休闲时间体育活动对肥胖的影响。 第四章涵盖了解释环境、社会和文化因素对肥胖影响的章节。本节中的章节关注农业和食品工业在当前肥胖流行病中所扮演的角色、肥胖的社会和经济方面、种族与文化的差异,以及环境污染物的影响。 第五部分探讨了肥胖的健康后果。该部分讨论了许多重要主题,包括肥胖与心脏病的关系、脂蛋白代谢、胰岛素抵抗和糖尿病、代谢综合征、癌症、肝脏生物学、肺功能、关节炎和痛风、心理健康和生活质量、儿童人群中的生长与健康问题以及对肥胖者的偏见和歧视。
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