植入牙科手术研究

English | 2023 | ISBN-10: 3031372336 | 463 pages| PDF (True) | 30 MB

This book explores, in a comprehensive and systematic manner, Surgical Research methodologies to the design and development of investigational studies in the field of implant-based oral rehabilitation. Such studies are linked in a chain binding in vitro, in vivo, ex vivo, and digital evaluations. An ambitious objective consists in exposing how investigators can generate and deliver knowledge by capturing synergy coming from preclinical and clinical trials. Accordingly, throughout the book, translational aspects are closely scrutinized. The opening chapters consider materials, methods and procedures for preclinical and clinical studies in which approaches and models are extensively described. The focus then moves to the process by which application of histology, biomechanics, biomarkers, cellular/molecular biology, and imaging technologies lead to new results and consequently novel treatment concepts in implant dentistry, implant borne prosthetic rehabilitations and the replacement or regeneration of tissues. Finally, the exciting opportunities afforded by the digital world are addressed. This book shall be a valuable resource and time-saving tool for a wide audience of researchers, students, practitioners, and academics.

这本书全面而系统地探讨了植入式口腔康复领域的实验研究方法，从设计和开发用于临床试验的研究。这些研究在体外、体内、体外以及数字评估之间形成了一个连接链条。其雄心勃勃的目标在于揭示研究人员如何通过捕捉前临床和临床试验之间的协同效应来生成并交付知识。因此，在整本书中，转化方面被密切审视。开篇章节考虑了用于前临床和临床研究的材料、方法和程序，并详细描述了这些领域的做法和模型。然后转向过程，即将组织学、生物力学、标志物、细胞/分子生物学以及成像技术应用于植入牙科、种植体支持的假体重建以及组织替代或再生等方面，从而导致新的结果并产生新的治疗概念。最后，本书探讨了数字化世界带来的令人兴奋的机会。这本书将成为广大研究人员、学生、从业者和学者的重要资源和时间节省工具。

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