酒精和与饮酒相关的疾病

English | 2023 | ISBN-10: 303132482X | 1630 pages| PDF (True) | 63 MB

Alcohol is one of the major risk factors for negative health outcomes worldwide. It accounts for more than 60 alcohol-related diseases, ranging from addiction, through liver cirrhosis, to cancer. Collectively, these conditions account for mortality and morbidity that make alcohol use one of the leading preventable causes of disability adjusted life-years (DALYs) lost globally. In this book, an international faculty covers all aspects of alcohol-related disorders, ranging from addiction/alcohol use disorders (AUD) to alcohol-related diseases of other organs such as liver, heart or cancer. A special focus is to reach out to primary care physicians who are in the front line of this major health problem. The book also provides an update for addiction specialists, as well as specialists in internal medicine, gastroenterology and hepatology. The book is divided into sections that include epidemiology, alcohol use disorders and addiction, alcohol-related liver disease, alcoholic hepatitis, primary care and interdisciplinary approaches and other alcohol-related diseases. Besides current diagnostic measures and treatment strategies, the book deals with the many underlying molecular and genetic mechanisms of alcohol toxicity. Novel insights include prospective data on all-cause mortality and the emerging major role of alcohol-mediated hemolysis and enhanced red blood cell turnover. The book also aims at guiding policy makers to handle the topic of alcohol in our society more responsibly.

酒精是全球范围内导致负面健康结果的主要风险因素之一。它包括了超过60种与酒精相关疾病，从成瘾、肝硬化到癌症。这些状况共同造成了死亡和残疾调整生命年（DALYs）损失，使饮酒成为全球防止可预防的致残率第二高的原因。在本书中，国际师资涵盖了所有相关的酒精相关障碍方面，从成瘾/酒精使用障碍（AUD）到其他器官如肝脏、心脏或癌症的相关酒精疾病。特别关注的是向主要健康问题的第一线初级保健医生传递信息。该书也为成瘾专家、内科医学专家、胃肠病学和肝病学专家提供了更新。本书分为多个章节，包括流行病学、酒精使用障碍与成瘾、酒精相关肝脏疾病、酒精性肝炎、初级保健和多学科方法以及其他相关的酒精疾病。除了当前的诊断措施及治疗方法外，该书还讨论了酒精毒性的许多底层分子和遗传机制。新见解还包括所有原因死亡数据的前瞻性数据以及由酒精引发溶血现象和红细胞周转加速的重大作用。本书也旨在为政策制定者提供指导，让他们能够更负责任地处理我们社会中的饮酒问题。

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