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以患者为中心的血液采样和定量分析

English | 2023 | ISBN: 1119615550 | 401 pages | True PDF EPUB | 16.28 MB

PATIENT CENTRIC BLOOD SAMPLING AND QUANTITATIVE ANALYSIS

Authoritative resource providing a complete overview of patient centric blood sampling, as well as its benefits and challenges

Patient Centric Blood Sampling and Quantitative Analysis focuses on the growing interest in alternative means to standard phlebotomy and analytical workflows for the collection and analysis of high-quality human biological samples for the quantitative determination of circulating drugs, their metabolites, and endogenous substances for clinical trials, routine healthcare and neonatal screening. The book clearly explains the benefits and constraints of having patients collect small volumes of blood in locations outside of a clinic (e.g at home), including: patient convenience; less invasive procedures; increased frequency of sampling; applicability to collecting samples from the young, elderly, and those in remote locations; greater frequency; and lower cost per sample. Readers will learn about approaches for successfully implementing patient centric sampling workflows in a number of scenarios, including the clinical setting and in the analytical laboratory.

Edited by four recognized experts in this field, with additional specialists in the discipline enlisted to write the component chapters, enabling greater depth and detail to be added and further raising the scientific standing of the publication, Patient Centric Blood Sampling and Quantitative Analysis includes information on

Basics of patient centric blood sampling and techniques and approaches that are available and in development for the collection and analysis of the samples Science behind patient centric blood sampling and its implications regarding human healthcare and wellbeing Application areas of patient centric sampling, including drug development, clinical chemistry/pathology, therapeutic drug monitoring, and more Practical approaches to successful implementation for existing and developing purposes and workflows, and case studies to support implementation within an organization

Giving the reader a broad understanding of what patient centric sampling is and where it might be applied for existing and potential future areas, Patient Centric Blood Sampling and Quantitative Analysis is an essential resource on the subject for many different types of laboratories, areas of clinical research and healthcare, including those in pharmaceutical, clinical, and research functions.


患者为中心的血液采样与定量分析

权威资源提供了一个关于患者为中心的血液采样的全面概述,以及它的好处和挑战。

患者为中心的血液采样与定量分析专注于人们对标准静脉穿刺和其他分析流程的兴趣增加,用于收集并分析高质量的人类生物样本,以量化确定循环药物、代谢物和内源性物质。这些样本主要用于临床试验、常规医疗保健和新生儿筛查等领域。本书清晰地解释了在诊所外(例如在家)采集小量血液样本的好处和限制,包括:患者便利;更少侵入性的操作;采样频率增加;适用于年轻人群、老年人以及偏远地区的样本收集;更高的频率;以及每份样品的成本更低。读者将学习如何在多种场景下成功实施患者为中心的采样工作流程,包括临床环境和分析实验室。

由这一领域四位公认专家编辑,并邀请了该学科的专业人士撰写章节,以增加深度和细节并进一步提高出版物的科学地位,《患者为中心的血液采样与定量分析》涵盖了:

患者中心血液采样的基础知识和技术方法,以及可用于收集和分析样本的方法

患者为中心的血液采样背后的科学及其对人类健康与福祉的影响

患者为中心的采样应用领域,包括药物开发、临床化学/病理学、治疗药物监测等领域

成功实施现有和未来目的及工作流程的实际方法,以及支持组织内实施案例研究

读者将获得对患者中心采样的全面理解及其在现有和潜在未来领域的适用性,《患者为中心的血液采样与定量分析》是许多不同类型的实验室、临床研究领域和医疗保健领域的重要资源,包括制药、临床和研究功能。


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