肿瘤铁氧化物基纳米平台的诊断治疗一体化:合成、代谢和毒性研究
This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.
这本书强调了处理癌症的最有效和最新方法,重点介绍了IONPs。书中描述了几种通过几种功能材料对IONPs表面进行精心设计的表面修饰过程,这导致多功能的基于IONPs的递送纳米平台的发展,这些平台提高了溶解度、稳定性和避免健康细胞的副作用。此外,还讨论了几种响应刺激的IONPs基策略。由于磁性、结构和热特性,IONPs本身可以用于磁靶向治疗、磁高温疗和光疗。在基于IONPs的免疫疗法、放疗和声动力疗法方面取得了显著进展,这些疗法可用于高效治疗癌症。最后,该书介绍了RIONs作为开发用于SPECT/MRI和PET/MRI应用的强大DMCA的基础平台。
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