甲状腺结节和分化型甲状腺癌的争议

English | 2023 | ISBN: 3031371348 | 392 Pages | PDF (True) | 8 MB

This book provides a practical, evidence-based approach to controversies in the management of thyroid nodules and differentiated thyroid cancer (DTC). Thyroid nodules are a commonly encountered clinical entity, identified in 2-6% of the population by palpation, and 20-35% by ultrasound. DTC is the solid organ cancer with the most rapidly increasing incidence (>50,000 new cases in the U.S. annually). Despite extensive research and multiple published comprehensive practice guidelines, numerous controversies remain within this field covering a wide range of issues, including incidence and epidemiology, radiographic evaluation, criteria for needle biopsy, cytopathologic and molecular diagnostics, active surveillance vs. operation for low-risk tumors, extent of surgery, indications for radioactive iodine treatment and external beam radiation, and optimal protocols for follow-up.

这本书提供了一种基于证据的实践方法来管理甲状腺结节和分化型甲状腺癌（DTC）中的争议。甲状腺结节是临床常见实体，在通过触诊被识别的人口中占2%-6%，而在通过超声检查中则占20%-35%。DTC是最容易发生率迅速上升的固体器官癌症（每年在美国有超过5万新病例）。尽管进行了广泛的研究和发布了多项全面的实践指南，该领域内仍存在许多争议问题，这些问题涵盖了广泛的议题，包括发病率和流行病学、影像学评估标准、针穿刺活检的标准、细胞病理和分子诊断标准、低风险肿瘤应采取观察而非手术治疗、手术切除的程度、放射性碘治疗及外部束辐射的适应症、以及最佳随访方案。

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