有机化合物以对抗 neglected tropical diseases 的合成最新进展

English | ISBN: 1608059030 | 2018 | 286 pages | PDF | 3 MB

The World Health Organization (WHO) has reported 14 diseases that are occurring exclusively in tropical areas. Most of these diseases are infectious and mainly affect poor populations. Some of these diseases include malaria, dengue fever, leishmaniasis and Chagas disease. Therefore, an acute need for increasing the arsenal of drugs is required to fight against these neglected diseases for the guaranteed recovery and relief of many patients. This E-book gathers important scientific research performed by scientists worldwide showing the state of the art of Medicinal Chemistry dedicated to the synthesis of compounds that are potentially bioactive against the causative agents of neglected diseases. The contents of this book include chapters on recent advances in synthetic organic compounds for the prevention of Chagas disease, recent advances in the discovery of small organic molecules for the prevention and treatment of dengue fever, leishmaniasis, leprosy, therapeutic arsenal and drug discovery for lymphatic filariasis, therapeutic agents for the treatment of malaria, schistosomiasis and synthetic organic compounds as potential antitubercular drugs. This book is intended for undergraduate and graduate students in institutes, colleges, universities and academies who want to specialize in the field of organic synthesis and medicinal chemistry. This book will also be a valuable resource of information for researchers in this field.

世界卫生组织（WHO）报告称，有14种疾病仅发生在热带地区。其中大多数是传染性的，并主要影响贫困人群。这些疾病包括疟疾、登革热、利什曼病和克劳斯达病。因此，对抗这些被忽视的疾病的武器库急需增加，以确保许多患者能够康复并得到缓解。这本电子书汇集了世界各地科学家进行的重要科学研究，展示了致力于合成对抗被忽视疾病致病原的有机化合物方面的最新技术。这本书包含关于通过预防利什曼病合成新的有机化合物所取得的最近进展、小分子有机化合物发现的近期进展以防止和治疗登革热、利什曼病、麻风病的治疗武器库及药物发现、淋巴丝虫病的治疗剂以及作为潜在抗结核药物的合成有机化合物等方面的章节。这本书旨在供各学院、大学、研究所和学院的学生使用，他们希望在有机合成和医药化学领域专门化。此外，这本电子书还将为该领域的研究人员提供有价值的信息资源。

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