甲状腺和大脑：理解甲状腺激素在脑发育和功能中的作用

English | 2024 | B0DJM9HGMZ | Pages: 512 | EPUB | 2.30 MB

This comprehensive textbook offers an in-depth exploration of how thyroid hormones influence brain development and function, particularly on cellular and molecular mechanisms. Readers will find current insights into the complex interplay between the thyroid and neurological systems, making it a valuable resource for researchers, advanced learners and clinicians in the fields of endocrinology, neuroscience, and developmental biology.

The book starts with a review of thyroid physiology, setting the stage for subsequent chapters that cover specific topics such as the impact of maternal thyroid hormones on fetal brain development and the effects of iodine deficiency. From here, the book progresses to cover the regulation of brain gene expression, neuronal and glial cell differentiation, and myelination by thyroid hormones, and how thyroid hormones shape the brain. Finally, the book addresses the link between thyroid dysfunction and mood disorders.

这本书提供了全面的探索甲状腺激素如何影响大脑发育和功能的内容，特别是从细胞和分子机制的角度。读者将找到关于甲状腺与神经系统之间复杂相互作用的当前见解，使其成为内分泌学、神经科学和发育生物学领域研究人员、高级学习者和临床医生的重要资源。 本书首先概述了甲状腺生理学，为后续章节中涵盖的具体主题铺垫，如母体甲状腺激素对胎儿脑发育的影响以及碘缺乏症的效果。从这里开始，本书继续覆盖甲状腺激素如何调节大脑基因表达、神经元和胶质细胞的分化，以及其对髓鞘化的作用，并解释甲状腺激素塑造大脑的方式。最后，本书探讨了甲状腺功能障碍与情绪障碍之间的联系。

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