Handbook of Clinical Neurology (From Volume 100 to Volume 203) (2011 TO 2024)

provides a basic outline of the field of interventional neuroradiology that is accessible to fellows, residents, clinicians and researchers in various disciplines, from diagnostic and interventional radiology to vascular neurology, general and vascular neurosurgery, and vascular biology. This volume offers a timely update to experienced clinical practitioners in a logical, easy-to-follow format. Content includes neurovascular anatomy, vascular biology, neurovascular physiology, vascular imaging, as well as sections on the diagnosis and therapeutic treatment of neurovascular disease. Explores the general scope of current clinical interventional neuroradiology, both for endovascular and percutaneous image-guided diagnosis and interventions in a variety of pathologies Defines basic physiological principles (e.g., cerebral perfusion pressure, intracranial pressure, vasospasm, tissue osmolality) with reference to those most essential to the management of neurovascular diseases Discusses pathophysiology and the unique challenges of pediatric cerebrovascular diseases, as well as endovascular and surgical therapies covers the effective treatment of migraines, including different subtypes of migraines in different patient populations. The classification and diagnostic criteria of common and uncommon subtypes of migraine is explored in detail, including childhood variants. An in-depth analysis of the pharmacology of acute and prophylactic agents is presented, along with an evidence-based review of pharmacologic management. This includes recently developed CGRP monoclonal antibodies and non-peptide small molecule CGRP antagonists. Advances in neuromodulatory treatments, both noninvasive and implantable are also critically reviewed. Finally, specific treatment-related issues in pregnancy and lactation and childhood as well as the elderly are covered. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness are also explored.

Summarizes evidence-based best treatment for migraines Differentiates treatment based on patient population, migraine type, and clinical setting Includes pharmacological, biobehavioral, and physical treatments Provides specialized treatments for children, the elderly, and pregnant patients

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